Cajun Garlic Butter Chicken with Creamy Parmesan Twisted Pasta

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Bold and buttery, this Cajun Garlic Butter Chicken with Creamy Parmesan Twisted Pasta is everything comfort food should be. Juicy, seared chicken thighs seasoned with zesty Cajun spice are nestled over a bed of rich, velvety pasta tossed in a garlic-Parmesan cream sauce. The twist pasta doesn’t just hold the sauce beautifully—it adds a playful texture that keeps each bite interesting.

Whether you’re cooking for a cozy date night or serving the whole family, this one-pan dinner is hearty, flavorful, and incredibly satisfying. It feels fancy enough for a special occasion but comes together quickly enough for weeknights. It’s the kind of dish that makes you want seconds before you’ve even finished the first plate.

Why You’ll Love This Cajun Garlic Butter Chicken with Creamy Parmesan Twisted Pasta

The flavor explosion is the biggest draw here. The Cajun spices bring just enough heat, balanced perfectly by the mellow creaminess of the Parmesan sauce. Garlic butter infuses both the chicken and pasta, layering richness throughout. The use of twisted pasta (like fusilli or rotini) ensures every bit of sauce clings to the noodles, making each forkful extra luscious.

Plus, it’s a one-skillet wonder that doesn’t require a long ingredient list or complicated steps. You can customize the spice level to your liking and even throw in some veggies like spinach or mushrooms if you’re feeling it.

What Kind of Pasta Should I Use?

Twisted pastas like rotini, fusilli, or gemelli are ideal because their spirals catch all that creamy, garlicky sauce. You can certainly use penne or even fettuccine if that’s what you have on hand, but the twists really do elevate the texture and mouthfeel. If you’re going gluten-free, opt for a sturdy GF pasta that holds up well in cream sauces—some of the lentil- or rice-based ones work great here.

Ingredients for the Cajun Garlic Butter Chicken with Creamy Parmesan Twisted Pasta

This dish brings together heat, creaminess, and bold savory flavors. The ingredient list is simple, but each item plays a crucial role in creating a well-balanced, delicious plate.

• Chicken thighs
• Cajun seasoning
• Butter
• Garlic cloves
• Heavy cream
• Parmesan cheese
• Twisted pasta (like rotini or fusilli)
• Olive oil
• Salt and pepper
• Fresh parsley (optional)

How To Make the Cajun Garlic Butter Chicken with Creamy Parmesan Twisted Pasta

Step 1: Season and Sear the Chicken

Start by patting the chicken thighs dry, then coat them generously with Cajun seasoning, salt, and pepper. Heat olive oil in a large skillet over medium-high heat, and sear the chicken for about 5-6 minutes per side until golden and cooked through. Remove from skillet and set aside.

Step 2: Cook the Pasta

Boil a large pot of salted water and cook your twisted pasta until al dente. Reserve about a cup of the pasta water before draining.

Step 3: Make the Garlic Butter Sauce

In the same skillet used for the chicken, melt butter and add minced garlic. Cook until fragrant, about 1 minute. Then pour in the heavy cream, stirring to deglaze the pan.

Step 4: Add Cheese and Combine

Lower the heat and stir in the grated Parmesan cheese until melted and smooth. Add a splash of reserved pasta water if the sauce feels too thick. Toss in the cooked pasta and coat it well in the sauce.

Step 5: Finish and Serve

Slice the Cajun chicken and lay it on top of the pasta. Garnish with freshly chopped parsley if desired and serve immediately while it’s hot and creamy.

How to Serve and Store Cajun Garlic Butter Chicken with Creamy Parmesan Twisted Pasta

This flavorful pasta dinner is perfect for serving right out of the skillet. It comfortably feeds 4 hungry eaters, making it a great weeknight staple or weekend treat. Plate it generously, making sure to scoop up that luscious sauce with every serving of pasta and chicken. For a fancier presentation, garnish with fresh parsley or even a light sprinkle of Cajun seasoning.

To store leftovers, let the dish cool completely and transfer it to an airtight container. It keeps well in the fridge for up to 3 days. When reheating, add a splash of milk or cream to loosen up the sauce and revive its creamy texture. A gentle reheat on the stovetop works best, but the microwave will do in a pinch.

What to Serve With Cajun Garlic Butter Chicken with Creamy Parmesan Twisted Pasta?

Garlic Bread

A crusty side of garlic bread is the classic companion to soak up the rich sauce.

Simple Green Salad

A crisp green salad with a light vinaigrette offers a refreshing contrast to the creamy pasta.

Roasted Broccoli

The slight bitterness of roasted broccoli pairs perfectly with the buttery Cajun flavor.

Sauteed Spinach

Adds greens to your plate without overpowering the bold flavors.

Grilled Asparagus

A seasonal favorite that brings a bright, earthy taste.

Parmesan Roasted Potatoes

For those who just can’t get enough Parmesan.

Corn on the Cob

Its natural sweetness makes a surprising but delightful contrast.

Lemon Water or Iced Tea

A clean, citrusy drink helps balance out the spice and creaminess.

Want More Chicken Pasta Ideas?

If you love this Cajun Garlic Butter Chicken with Creamy Parmesan Twisted Pasta, check out these equally comforting and flavor-packed recipes:

• Garlic Butter Chicken Balls with Creamy Parmesan Pasta when you want savory, bite-sized comfort.
• Quick Creamy Cajun Pasta for a fast and spicy midweek winner.
• Smothered Chicken and Rice if you’re craving something heartier and saucy.
• Hawaiian Pineapple Chicken Rice for a sweet-savory twist.
• Cowboy Butter Chicken Linguine with smoky depth and garlic butter indulgence.

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And let me know in the comments how yours turned out! Did you go extra on the spice? Did you add a green twist like spinach or zucchini?

I love hearing how others make these recipes their own. Don’t be shy about sharing tips or questions—let’s help each other cook better together.

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Conclusion

Cajun Garlic Butter Chicken with Creamy Parmesan Twisted Pasta is a dish that brings bold flavor, cozy richness, and satisfying texture all in one skillet. With pantry-friendly ingredients and a quick cook time, it’s an ideal recipe to keep in rotation. Whether you make it for guests or just a Tuesday night, it’s guaranteed to please every time.

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