Name: Sicilian Meatloaf
Prep time: 20 min
Cook time: 1 h
Total time: 1 h 20 min
Cuisine: Italian
Ingredients: 1 lb ground beef; 1 lb ground pork; 1 cup breadcrumbs; 2 eggs; 1/2 cup grated parmesan cheese; 3 cloves garlic, minced; 1/4 cup chopped fresh parsley; 2 cups fresh spinach; 1/2 cup roasted red peppers, chopped; 1 1/2 cups shredded mozzarella cheese; 1 tsp salt; 1/2 tsp black pepper; 2 tbsp olive oil

Sicilian meatloaf is where comfort meets elegance in the most satisfying way. Unlike traditional meatloaf, this Italian-inspired version is packed with bold flavors, gooey cheeses, and a savory blend of herbs that will make your whole kitchen smell like a Sunday at Nonna’s house. It layers in meats, cheese, and vegetables like a rolled-up lasagna but with a much simpler process and stunning result.

What sets this dish apart is its hearty stuffing and that deliciously browned crust that locks in moisture. Every slice has a surprise in the center, thanks to the melty mozzarella and sautéed vegetables wrapped inside. Whether you serve it at a family gathering or slice it cold the next day for sandwiches, Sicilian meatloaf never disappoints.

Why You’ll Love This Sicilian Meatloaf

This meatloaf is a weeknight hero and a Sunday dinner showstopper. The filling is where the magic happens—it’s loaded with spinach, roasted red peppers, and gooey cheese. The outside bakes to golden perfection, holding everything together like a warm, crispy hug. It’s easy to prepare, makes great leftovers, and feels special enough for guests.

What Kind of Ground Meat Should I Use?

A blend of ground beef and ground pork works wonderfully in this recipe, offering both flavor and tenderness. You can substitute turkey or chicken for a leaner version, but keep in mind it may not be as rich. The key is to balance moisture and fat, so you get a meatloaf that’s juicy without being greasy.

Ingredients for the Sicilian Meatloaf

The magic of Sicilian meatloaf comes from layering simple ingredients into something spectacular. Each item plays a crucial role in flavor and texture.

Ground beef

Ground pork
Breadcrumbs
Eggs

Parmesan cheese
Garlic
Parsley

Spinach
Roasted red peppers
Mozzarella cheese

Salt and pepper
Olive oil

Each component brings something essential. Ground beef provides structure, while ground pork adds richness. Breadcrumbs and eggs bind it all together, and parmesan gives it that signature umami kick. Garlic and parsley freshen the mix, while the spinach and roasted red peppers make the filling bright and juicy. Mozzarella melts into a creamy pocket inside. And a drizzle of olive oil before baking gives that perfect browned crust.

How To Make the Sicilian Meatloaf

Step 1: Sauté the Vegetables

Start by sautéing spinach, garlic, and roasted red peppers in a bit of olive oil until tender. Set aside to cool.

Step 2: Mix the Meat Mixture

In a large bowl, combine ground beef, ground pork, breadcrumbs, eggs, parmesan, parsley, salt, and pepper. Mix gently to avoid overworking.

Step 3: Layer and Roll

Spread the meat mixture on parchment paper into a large rectangle. Layer the sautéed vegetables and mozzarella over the top. Carefully roll it into a loaf using the paper to guide you.

Step 4: Bake to Perfection

Transfer to a baking dish and drizzle olive oil over the top. Bake at 375°F (190°C) for 45–60 minutes, or until the center reaches 160°F (71°C).

Step 5: Rest and Slice

Let the meatloaf rest for 10 minutes before slicing to lock in the juices.

Serving and Storing Sicilian Meatloaf

This meatloaf easily feeds 6 to 8 people and is great for make-ahead meals. Serve it fresh from the oven for dinner, or chill leftovers and reheat slices throughout the week. It also tastes amazing cold, sandwiched between crusty bread with a smear of marinara.

To store, wrap tightly in foil or place in an airtight container in the fridge for up to 4 days. It also freezes well. Just slice and separate with parchment before freezing for easy grab-and-go meals.

What to Serve With Sicilian Meatloaf?

Garlic Mashed Potatoes

Creamy mashed potatoes with a hit of garlic pair beautifully with the rich flavors of this meatloaf.

Roasted Broccolini

A simple roasted green veggie adds balance and color to your plate.

Balsamic Glazed Carrots

The sweetness of balsamic-glazed carrots brings a delightful contrast to the savory meat.

Crusty Italian Bread

Perfect for sopping up any juices or enjoying cold meatloaf slices later.

Arugula Salad

A light salad with lemon vinaigrette helps cut through the richness.

Sauteed Zucchini

Mild, buttery zucchini is a quick stovetop veggie that matches the Sicilian profile.

Tomato Basil Soup

A small bowl of this soup on the side brings extra comfort.

Want More Italian-Inspired Comfort Food?

If this Sicilian meatloaf has you craving more Italian-inspired comfort, check out these irresistible favorites:

Save This Recipe For Later

📌 Save this recipe to your Pinterest dinner board so you can find it fast whenever the craving hits.

Let me know in the comments if you added a twist! Maybe more cheese? Extra herbs? I love seeing how you make it your own.

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Conclusion

Sicilian meatloaf turns a humble classic into a showstopping centerpiece that’s juicy, cheesy, and full of Old World flavor. With just a few pantry staples and a handful of fresh ingredients, you get a meal that feels like a warm hug from Sicily itself. Whether it’s Sunday dinner or a make-ahead weeknight win, this is a recipe you’ll come back to again and again.

Sicilian Meatloaf

Why You’ll Love This Sicilian Meatloaf

What Kind of Ground Meat Should I Use?

Ingredients for the Sicilian Meatloaf