Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce

WANT TO SAVE THIS RECIPE?

If you’re in the mood for comfort food that doesn’t shy away from bold flavor, this creamy Velveeta penne pasta with Cajun beef Alfredo sauce is a must-try. Velveeta brings that smooth, velvety texture everyone craves, and when it meets the richness of homemade Alfredo sauce and the spicy kick of Cajun-seasoned beef, magic happens. It’s indulgent, hearty, and perfect for when you want to treat yourself or impress your dinner guests with something unexpectedly delicious.

This dish combines everything we love about pasta night: creamy sauce, tender meat, and pasta that perfectly soaks up every bit of flavor. The Cajun spices add a welcome heat without being overpowering, balancing the creaminess of the Velveeta. It’s a satisfying, cozy bowl that checks every box for a delicious weeknight dinner or a weekend comfort meal.

Why You’ll Love This Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce

This dish hits all the right notes of creamy, spicy, and savory in one spoonful. It’s a fuss-free meal that still feels like a restaurant-quality plate. The recipe doesn’t require tons of ingredients, and yet the flavor complexity will surprise you. If you’re a fan of Alfredo but want something new with a little Southern twist, this one is a no-brainer.

Velveeta melts like a dream, coating the penne perfectly and mingling with the Cajun beef to create a sauce that’s both comforting and exciting. Plus, this dish is easy to scale for families or dinner parties, and leftovers reheat beautifully for lunch the next day.

What Kind of Pasta Should I Use?

Penne pasta is a great choice for this recipe because its tubular shape holds onto the creamy Alfredo sauce well, giving you that saucy bite every time. But you could easily swap it with rigatoni, ziti, or even fusilli if that’s what you have on hand. The key is to choose a pasta that has enough surface or texture to grab onto the cheese sauce and beef bits.

Ingredients for the Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce

This recipe leans on a handful of flavorful ingredients that come together effortlessly to build a decadent pasta dish. Each component plays a key role in creating that creamy, spicy, and savory harmony.

• Penne pasta
• Velveeta cheese
• Heavy cream
• Cajun seasoning
• Ground beef
• Garlic cloves
• Butter
• Salt
• Black pepper
• Grated Parmesan cheese

How To Make the Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce

Step 1: Cook the Penne

Bring a large pot of salted water to a boil. Cook the penne pasta according to package instructions until al dente. Drain and set aside.

Step 2: Brown the Cajun Beef

In a large skillet, melt butter over medium heat. Add ground beef and sprinkle in Cajun seasoning. Cook until the beef is browned and slightly crispy around the edges. Add minced garlic and sauté for another minute.

Step 3: Make the Velveeta Alfredo Sauce

Lower the heat and pour in the heavy cream. Stir in Velveeta cheese, cubed, and let it melt into a smooth sauce. Add a pinch of salt and black pepper to taste. For added depth, sprinkle in some grated Parmesan.

Step 4: Combine Everything

Add the cooked penne to the skillet and gently fold everything together until the pasta is evenly coated with the creamy Cajun beef Alfredo sauce.

Step 5: Serve

Plate up while hot and garnish with a little extra Parmesan or a dash of Cajun seasoning if you love heat. Serve immediately and enjoy that irresistible creamy-spicy goodness.

Serving and Storing Creamy Velveeta Penne Pasta with Cajun Beef Alfredo Sauce

This dish is incredibly rich and satisfying, so it easily feeds 4 to 6 people depending on portion sizes. Serve it hot, straight from the skillet, with a light garnish of Parmesan or fresh herbs if you like a pop of green. For a casual dinner or potluck, it holds its own beautifully as a main course without needing much else on the side.

To store leftovers, transfer the pasta to an airtight container and refrigerate for up to 3 days. The sauce will thicken as it sits, but a splash of milk or cream when reheating will help bring it back to life. Simply warm it on the stovetop or in the microwave until creamy and hot.

What to Serve With Creamy Velveeta Penne Pasta?

Garlic Bread

Warm, buttery garlic bread is perfect for soaking up the extra sauce and adds a crispy contrast to the creamy pasta.

Caesar Salad

The tanginess and crunch of a Caesar salad help balance out the richness of the Alfredo sauce.

Roasted Broccoli

Slightly charred broccoli adds an earthy note that complements the Cajun spice and creaminess.

Grilled Corn on the Cob

Sweet and smoky grilled corn adds freshness and texture that pair beautifully with this dish.

Fried Green Tomatoes

Their crispy coating and slight tartness cut through the creaminess in the best way.

Pickled Jalapeños or Vegetables

If you like an extra kick, the acidity and spice of pickled veggies contrast well with the cheese sauce.

Sparkling Water or Lemonade

For drinks, a light and zesty option helps keep the meal from feeling too heavy.

Fresh Fruit Salad

Something like melon, berries, or pineapple makes a refreshing finish after the richness of the pasta.

Want More Pasta Ideas with a Twist?

If this creamy Velveeta penne pasta with Cajun beef Alfredo sauce had you going back for seconds, we’ve got plenty more where that came from. Here are a few more comforting, creative, and craveable pasta dishes to explore:

• Try our Delicious Garlic Sausage Alfredo Rigatoni for another rich and hearty meal.
• Looking for spice? Our Quick Creamy Cajun Pasta Recipe brings serious heat and simplicity.
• Craving shrimp? This Creamy Garlic Butter Shrimp Scampi Lasagna layers creamy seafood indulgence.
• For something with a Mediterranean vibe, the Flavorful Mediterranean Steak Bowls are packed with punchy herbs and lean protein.
• Don’t miss the Garlic Butter Chicken Balls with Creamy Parmesan Pasta if you love cheesy chicken goodness.

Save This Recipe For Later

📌 Save this recipe to your Pinterest dinner board so you can revisit this comfort classic anytime.

And when you make it, let us know how it turned out! Did you tweak the spice or add veggies? Share your spin in the comments so we can swap ideas and keep the deliciousness flowing.

Explore beautifully curated health-boosting dinners and indulgent pasta favorites on Luna Meals on Pinterest — your go-to for recipes that hit the spot and make you feel amazing!

Conclusion

Creamy Velveeta penne pasta with Cajun beef Alfredo sauce is everything comfort food should be: rich, spicy, cheesy, and deeply satisfying. It brings together pantry staples and bold Cajun flavor into one dreamy dish that you’ll want to make again and again. Whether it’s a weeknight craving or a meal to impress, this pasta has your back.

Print

WANT TO SAVE THIS RECIPE?