Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

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If you crave something rich, spicy, and extra cheesy, this Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is the weeknight dinner upgrade your taste buds deserve. Juicy seared chicken tossed with tender spaghetti and drenched in a silky garlic-mozzarella sauce creates a perfect harmony of heat and comfort. This dish brings restaurant-quality flavor straight to your table with ingredients you probably already have in your kitchen.

Every forkful of this pasta hits you with bold Cajun spice, balanced by a mellow creaminess that clings to every strand of spaghetti. It’s simple enough to make on a busy night but luxurious enough to impress guests. If you’re into recipes that balance cozy familiarity with a little culinary edge, this one is going straight into your rotation.

Why You’ll Love This Creamy Cajun Chicken Spaghetti

This dish has it all: spice, cream, and cheese, wrapped into a single comforting bowl. The Cajun seasoning gives it an exciting kick, while the creamy garlic sauce smooths everything out without feeling heavy. It’s one of those meals that feels indulgent yet homey. Perfect for family dinners, date nights, or just when you’re in need of a flavorful pick-me-up.

What Kind of Pasta Should I Use?

Spaghetti works wonderfully for this dish because its shape allows it to capture the creamy sauce in every bite. But if you’re in the mood to experiment, fettuccine, linguine, or even penne can work beautifully. Just make sure it’s a pasta that can hold up to the richness of the sauce and the heartiness of the chicken.

Ingredients for the Creamy Cajun Chicken Spaghetti

This recipe layers spice, richness, and indulgence through carefully selected ingredients. The Cajun seasoning is the heartbeat of this dish, while the mozzarella-garlic sauce brings the magic that ties it all together. You don’t need anything fancy, just quality staples that deliver flavor.

• Spaghetti
• Chicken breast
• Olive oil
• Cajun seasoning
• Salt and pepper
• Garlic cloves
• Unsalted butter
• All-purpose flour
• Whole milk
• Shredded mozzarella cheese
• Parmesan cheese
• Heavy cream
• Fresh parsley

How To Make the Creamy Cajun Chicken Spaghetti

Step 1: Season and Sear the Chicken

Start by seasoning chicken breasts with Cajun spice, salt, and pepper. In a hot skillet with a drizzle of olive oil, sear them until golden on both sides and fully cooked through. Remove and let rest before slicing.

Step 2: Cook the Pasta

Boil a large pot of salted water and cook the spaghetti according to the package instructions. Drain and set aside, reserving a cup of pasta water.

Step 3: Make the Garlic Mozzarella Sauce

In the same skillet, melt butter and sauté minced garlic until fragrant. Stir in flour and whisk until it forms a roux. Slowly pour in milk and whisk until smooth. Add mozzarella and Parmesan cheese, stirring until melted. Pour in heavy cream and simmer until thickened. Season to taste.

Step 4: Toss and Combine

Add the cooked spaghetti to the sauce, tossing well to coat. If the sauce is too thick, add a splash of the reserved pasta water. Top with sliced Cajun chicken and sprinkle fresh parsley over the top.

Step 5: Serve Hot

Serve immediately while the sauce is creamy and warm. A sprinkle of extra Parmesan never hurts!

How to Serve and Store Creamy Cajun Chicken Spaghetti

This spicy and creamy pasta is best served hot and fresh from the skillet, when the sauce is velvety and the flavors are at their peak. It generously feeds four hungry people, making it a great option for weeknight dinners or casual gatherings. Serve it in deep bowls with a sprinkle of Parmesan and chopped parsley for a cozy, satisfying meal.

To store leftovers, allow the pasta to cool completely and transfer to an airtight container. Refrigerate for up to 3 days. When reheating, add a splash of milk or cream to help loosen the sauce and revive its silky texture. A quick zap in the microwave or a gentle reheat on the stove does the trick.

What to Serve With Creamy Cajun Chicken Spaghetti?

Garlic Bread

Crunchy and buttery garlic bread is the perfect partner for soaking up every last bit of that luscious sauce.

Simple Green Salad

A crisp green salad with a tangy vinaigrette brings freshness and balance to the richness of the dish.

Roasted Broccoli

Lightly charred roasted broccoli adds a nice contrast in flavor and texture to the creamy pasta.

Sauteed Spinach

Quickly wilted spinach with a squeeze of lemon provides a fresh and slightly bitter note to complement the Cajun spices.

Grilled Corn on the Cob

Sweet and smoky grilled corn enhances the Southern vibe and offers a fun, casual touch.

Creamy Coleslaw

For a crunchy, cool side, serve a classic coleslaw to mellow the heat of the Cajun seasoning.

Balsamic Roasted Tomatoes

Tangy-sweet roasted tomatoes bring a pop of color and acidity that works beautifully alongside the rich mozzarella sauce.

Want More Pasta Dinner Ideas?

If this Creamy Cajun Chicken Spaghetti has you hooked on comforting dinners with a flavorful kick, you’ll love these other crave-worthy options:

• Try this cozy Delicious Garlic Sausage Alfredo Rigatoni if you want a garlicky spin with a sausage twist.
• For something with extra zest, check out our Quick Creamy Cajun Pasta Recipe for a faster, meatless version.
• Enjoy a hearty mix with the Smothered Chicken and Rice to satisfy both comfort food cravings and Southern soul.
• Our Creamy Mushroom Ravioli delivers rich earthiness with a luxurious bite.
• Or go big on flavor with this Garlic Butter Chicken Balls with Creamy Parmesan Pasta for a next-level dinner treat.

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📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

And let me know in the comments how yours turned out! Did you add some extra heat? Maybe swapped in shrimp or mushrooms instead? I love hearing how you make each dish your own.

Explore beautifully curated health-boosting meals and comfort food classics on Luna Meals on Pinterest and discover your new weeknight go-to!

Conclusion

Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is the perfect blend of spice, creaminess, and comfort. Whether you’re serving it on a busy weeknight or making it for friends, this dish is guaranteed to leave everyone asking for seconds. Easy to make, endlessly customizable, and packed with bold flavor, it’s everything pasta night should be.

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