Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta

If there’s one dish that hits every craving at once, it’s this Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta. It’s bold, creamy, spicy, and lusciously cheesy all in one twirl of pasta. From the moment the Cajun spices hit the skillet, your kitchen will be filled with the kind of aroma that brings everyone to the table.
Twisted pasta locks in the rich Alfredo Velveeta sauce, while garlicky undertones and spicy Cajun beef give each bite a punch of flavor. Whether you’re making this for a cozy night in or looking to impress guests with something a little different, this recipe checks every box. It’s a comforting Southern-style meal with a modern, cheesy twist.
Why You’ll Love This Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
This pasta is not just filling, it’s indulgent in the best way. The creamy Alfredo Velveeta gives it a melty, velvety texture while the Cajun seasoning brings depth and a little heat. It’s a full-on comfort meal that still feels exciting and new. It’s also simple to pull together and uses pantry staples, making it an easy go-to on busy nights.
Whether you’re a fan of Cajun cuisine or just looking to elevate your weeknight pasta game, this one hits all the right notes. Perfectly seasoned beef, buttery garlic, and creamy cheese make it irresistible.
What Kind of Pasta Works Best with Alfredo and Cajun Beef?
Twisted pasta like rotini or fusilli is ideal for this dish. The grooves and spirals are perfect for catching the creamy Alfredo Velveeta sauce and bits of spiced ground beef. If you prefer a more traditional pasta shape, penne or even cavatappi work well too. Just make sure the pasta can hold its own against the richness of the sauce and meat, and you’ll be set.
Ingredients for the Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
This flavor-packed pasta dish comes together with a handful of bold, creamy, and comforting ingredients. Each element plays a key role in building the layers of flavor. Here’s what you’ll need:
- Twisted pasta (rotini or fusilli): These shapes are perfect for grabbing and holding onto all the sauce.
- Ground beef: The Cajun-seasoned protein base that gives the dish its hearty kick.
- Cajun seasoning: Adds smoky heat and depth to the beef.
- Fresh garlic: Infuses the base with rich, savory aroma.
- Velveeta cheese: Melts beautifully for that signature creamy texture.
- Heavy cream: Helps create the silky Alfredo-style sauce.
- Butter: Enhances the garlic flavor and adds depth to the sauce.
- Parmesan cheese: Adds a salty, nutty finish that sharpens the creamy sauce.
- Salt and black pepper: To balance and round out the flavors.


How To Make the Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
Step 1: Cook the Pasta
Bring a large pot of salted water to a boil and cook the twisted pasta until al dente according to package instructions. Drain and set aside.
Step 2: Brown the Beef with Cajun Flavor
In a large skillet over medium heat, cook the ground beef until browned and cooked through. Drain excess fat, then add Cajun seasoning and minced garlic. Cook for another 2 minutes to let the spices bloom.
Step 3: Build the Creamy Cheese Sauce
Reduce the heat to low. Add butter and let it melt into the beef mixture. Stir in heavy cream and cubed Velveeta. Stir continuously until the cheese is fully melted and sauce is smooth.
Step 4: Toss in the Pasta
Add the cooked pasta to the skillet and stir well to coat. Let everything simmer together for a few minutes to absorb flavor. Add Parmesan cheese and stir again.
Step 5: Taste and Serve
Season with salt and black pepper to taste. Serve hot and garnish with a bit more Parmesan if desired. Enjoy the layers of creamy, garlicky, cheesy, and spicy goodness in every bite!
How to Serve and Store Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
This dish is definitely a meal that satisfies on its own, but it can also be the centerpiece of a cozy dinner spread. It feeds about 4 to 6 people depending on portion size, making it perfect for family dinners or a casual gathering with friends.
To serve, scoop the hot pasta into bowls and finish with extra Parmesan or a sprinkle of chopped parsley for a pop of freshness. The cheesy sauce does best when served immediately, but it holds up well for seconds and even reheating.
Store any leftovers in an airtight container in the refrigerator for up to 3 days. When reheating, add a splash of cream or milk to revive the sauce and stir until it’s creamy again.
What to Serve With Cheesy Garlic Twisted Pasta?
Garlic Bread with a Twist
Double down on the garlic with a side of buttery garlic knots or cheesy garlic toast. They soak up that extra Alfredo sauce like a dream.
Simple Green Salad
A crisp romaine or arugula salad with a tangy vinaigrette helps balance the richness of the dish.
Roasted Broccoli or Asparagus
Add a roasted veggie side to bring in some color and extra nutrition.
Creamy Coleslaw
Its crunch and slight tang play nicely with the spicy Cajun beef.
Sweet Corn on the Cob
Lightly grilled corn pairs beautifully with the creamy, cheesy sauce and adds a sweet contrast.
Fried Okra
Bring in some Southern comfort with crispy, golden fried okra on the side.
Pickled Jalapeños or Banana Peppers
If you like spice, a small bowl of pickled peppers on the table is a fantastic topping for the pasta.
Sweet Tea or Lemonade
Round out the meal with a cold, refreshing drink that cools down the Cajun heat.
Want More Pasta Ideas with a Twist?
If this Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta has you dreaming of more creamy, savory comfort meals, check out these other delicious options from Luna Meals:
• Try this ultra-creamy and savory Delicious Garlic Sausage Alfredo Rigatoni when you’re craving a bold garlic-forward flavor.
• For a little heat and a faster weeknight fix, you’ll love the Quick Creamy Cajun Pasta.
• In the mood for something indulgent? This Creamy Garlic Butter Shrimp Scampi Lasagna layers comfort and elegance.
• If you’re all about fusion, don’t miss the Cowboy Butter Chicken Linguine for smoky, buttery bliss.
• And for a lighter, refreshing pasta bowl, the Light Lemon Basil Pasta Salad with Chicken offers a bright and zesty contrast.
Save This Recipe For Later
📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.
And let me know in the comments how yours turned out. Did you go spicy or keep it mellow? Did you mix in other veggies or switch up the cheese?
I love hearing how others make these recipes their own. Questions are welcome too — let’s help each other cook better, together.
Explore more comforting, cheesy, and flavor-packed recipes on Luna Meals on Pinterest and find your next dinner obsession!
Conclusion
Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta is a celebration of flavor. It takes simple ingredients and turns them into something magical. Whether you’re cooking to impress or just feeding hungry mouths at home, this dish always delivers. Comforting, creamy, spicy, and endlessly satisfying — make it once and you’ll keep coming back to it.


Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
- Total Time: 25 minutes
- Yield: 4 to 6 servings
Description
This Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta is the ultimate comfort food with a Southern twist. Loaded with creamy Velveeta Alfredo, savory garlic, and spicy Cajun ground beef, it’s a rich and flavorful pasta recipe that’s perfect for weeknight dinners or cozy gatherings. A bold and cheesy meal that comes together in under 30 minutes!
Ingredients
16 oz twisted pasta (rotini or fusilli)
1 lb ground beef
2 tbsp Cajun seasoning
4 cloves garlic, minced
8 oz Velveeta cheese, cubed
1 cup heavy cream
2 tbsp butter
1/3 cup grated Parmesan cheese
Salt, to taste
Black pepper, to taste
Instructions
1. Bring a large pot of salted water to a boil and cook the pasta until al dente. Drain and set aside.
2. In a large skillet over medium heat, brown the ground beef until fully cooked. Drain the fat.
3. Add Cajun seasoning and minced garlic to the skillet. Stir and cook for 2 more minutes to infuse the flavor.
4. Reduce heat to low, add butter, and melt into the beef mixture. Pour in heavy cream and add Velveeta cubes. Stir until melted and smooth.
5. Add the cooked pasta into the skillet and toss until fully coated in the sauce.
6. Stir in the Parmesan cheese and let everything simmer for 2–3 minutes.
7. Season with salt and pepper to taste. Serve hot with extra Parmesan if desired.
Notes
This dish tastes best fresh, but reheats well with a splash of cream.
Feel free to swap the beef for chicken or plant-based protein for variety.
For extra heat, add crushed red pepper flakes or a drizzle of hot sauce.
- Prep Time: 10 minutes
- Cook Time: 15 minutes
- Category: Pasta
- Method: Stovetop
- Cuisine: American, Cajun-inspired
Nutrition
- Serving Size: 1 bowl
- Calories: 640
- Sugar: 4g
- Sodium: 910mg
- Fat: 38g
- Saturated Fat: 19g
- Unsaturated Fat: 16g
- Trans Fat: 0.5g
- Carbohydrates: 47g
- Fiber: 2g
- Protein: 29g
- Cholesterol: 110mg
