Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce

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Imagine twirling a forkful of creamy Alfredo-coated bowtie pasta, then catching a bite of tender Cajun-spiced chicken, all infused with a golden garlicky aroma and melty cheese. This dish doesn’t just satisfy hunger—it soothes the soul. It’s a comfort meal that doesn’t ask for too much effort but delivers flavor like a five-star dinner.

Whether you’re making dinner for a hungry family or spicing up your usual weeknight rotation, Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce checks every box. It balances smoky heat, creamy richness, and cheesy goodness with every bite. Plus, the bowtie pasta adds a playful twist that makes the meal feel fun and indulgent.

Why You’ll Love This Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce

This dish is the perfect fusion of bold Cajun flavor and Italian indulgence. It gives you that creamy, cheesy comfort you crave, but the garlic and Cajun spices kick it up a notch. You get a full, hearty meal with protein, carbs, and dairy all in one skillet. Best of all, it comes together in under 45 minutes—ideal for busy nights without sacrificing taste.

What Kind of Pasta Should I Use?

Bowtie pasta (also known as farfalle) is ideal because its wide surface area holds onto the sauce beautifully, and it adds a whimsical look to the plate. However, if you’re out of bowties, penne or rotini are great alternatives. You want a pasta shape with crevices or texture to capture all that rich Alfredo and cheesy goodness.

Ingredients for the Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce

To bring out the best in this indulgent dish, each ingredient plays a flavorful role. The Cajun seasoning brings warmth and spice, while the Alfredo sauce delivers that creamy, comforting hug. The cheese, garlic, and bowtie pasta tie it all together into a decadent bowl of happiness.

• Bowtie pasta
• Chicken breast
• Cajun seasoning
• Garlic cloves
• Heavy cream
• Parmesan cheese
• Mozzarella cheese
• Butter
• Olive oil
• Salt
• Black pepper

How To Make the Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce

Step 1: Season and Sear the Chicken

Start by slicing your chicken breast into thin strips or bite-sized chunks. Coat them generously with Cajun seasoning, salt, and pepper. In a large skillet over medium-high heat, add olive oil and sear the chicken until golden brown and fully cooked. Remove the chicken and set it aside.

Step 2: Cook the Pasta

Boil a pot of salted water and cook the bowtie pasta until al dente. Drain and set aside, reserving about a half cup of pasta water in case you need to loosen the sauce later.

Step 3: Make the Garlic Alfredo Sauce

In the same skillet you used for the chicken, reduce the heat to medium and melt butter. Add minced garlic and sauté until fragrant. Pour in the heavy cream and let it simmer for a few minutes before stirring in the Parmesan and mozzarella cheeses until smooth and creamy.

Step 4: Combine Everything

Return the cooked chicken to the skillet and stir to coat in the Alfredo sauce. Add the pasta and gently toss until everything is coated and well combined. If the sauce is too thick, use the reserved pasta water to loosen it slightly.

Step 5: Serve Hot and Cheesy

Serve immediately while everything is hot and melty. Optionally, garnish with chopped parsley or a little extra Parmesan on top for good measure.

How to Serve and Store Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce

This rich and hearty pasta dish is best served hot and fresh off the stove. The creamy Alfredo sauce hugs each bowtie just right when it’s still warm and melty. It makes a filling meal for 4 to 5 people, especially when paired with a light side or salad.

If you find yourself with leftovers, store them in an airtight container in the refrigerator for up to 3 days. To reheat, add a splash of milk or cream and warm it gently on the stovetop or in the microwave. This will help bring the sauce back to its creamy consistency without drying it out.

What to Serve With Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce?

Garlic Bread or Toasted Baguette

A slice of crispy garlic bread or a warm baguette is perfect for scooping up every last bit of sauce.

Green Salad with Lemon Vinaigrette

Balance the richness with something light and zesty. A crisp salad adds freshness and cuts through the creamy sauce.

Roasted Broccoli or Asparagus

These roasted veggies bring a bit of char and texture that pairs beautifully with the pasta’s creamy base.

Parmesan-Crusted Zucchini Rounds

Another fun and cheesy side that complements the Cajun heat without overpowering it.

Southern Corn Fritters

Add a Southern-inspired crunch to your plate with sweet corn flavor that contrasts the spice just right.

Creamy Mushroom Sauce for Steak (or on the side)

This works as a luxurious drizzle over the pasta or alongside a protein-rich second course.

Skillet-Fried Eggplant

Adds heartiness and a crispy texture while staying vegetarian-friendly.

Sparkling Lemon Water or Iced Tea

Keep it light with a refreshing drink to cool things off and refresh your palate.

Want More Pasta Ideas with a Twist?

If you can’t get enough of this creamy Cajun pasta, we’ve got more pasta recipes that deliver big on flavor:

• Try the bold flavors in our Quick Creamy Cajun Pasta Recipe if you want more smoky heat with less fuss.
• The Delicious Garlic Sausage Alfredo Rigatoni brings savory sausage and garlic together in an ultra-satisfying way.
• If shrimp is your thing, the Creamy Garlic Butter Shrimp Scampi Lasagna will totally wow you.
• Looking for something cozy? Creamy Mushroom Ravioli is earthy, rich, and comforting.
• Or go for a lighter twist with our Light Lemon Basil Pasta Salad with Chicken that still brings bold flavor in a fresh way.

Save This Recipe For Later

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

And let me know in the comments how yours turned out. Did you use extra Cajun spice? Add bell peppers or mushrooms? Swap in shrimp instead of chicken?

I love hearing how you make these recipes your own. Got questions? Let’s talk pasta!

Explore beautifully curated health-boosting meals and more comforting dishes on Luna Meals on Pinterest and discover your next crave-worthy favorite.

Conclusion

Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce is everything you want in a dinner: bold flavor, creamy richness, and cheesy comfort in every bite. Whether you’re making it for a cozy night in or to impress guests with a no-fuss wow factor, this dish brings the magic to your table. It’s a warm hug with a little Southern spice—what’s not to love?

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